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3,5-Di-O-caffeoylquinic acid

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Antioxidant

Antioxidant. Shows antiproliferative activity.

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Alternative Name	3,5-CQA, Isochlorogenic acid
Appearance	Off-white to yellow/brown crystalline solid.
CAS	2450-53-5
Formula	C₂₅H₂₄O₁₂
Identity	Determined by 1H-NMR, 13C-NMR and MS.
MW	516.5
Purity	≥97% (HPLC)
Solubility	Soluble in DMSO or 100% ethanol.
Source	Isolated from Cynara scolymus.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Ethanol extract of Chrysanthemum zawadskii inhibits the NLRP3 inflammasome by suppressing ASC oligomerization in macrophages: A.R. Jang, et al.; Exp. Ther. Med. 25, 128 (2023), Abstract
Changes in caffeic acid derivatives in sweet potato (Ipomoea batatas L.) during cooking and processing: M. Takenaka, et al.; Biosci. Biotechnol. Biochem. 70, 172 (2006), Abstract — Full Text
Antioxidant and antiproliferative activities of sweet potato (Ipomoea batatas [L.] Lam Tainong 57″)”””: D.J. Huang, et al.; Bot. Bull. Acad. Sinica 45, 179 (2004)
In vitro antioxidative effects and tyrosinase inhibitory activities of seven hydroxycinnamoyl derivatives in green coffee beans: K. Iwai, et al.; J. Agric. Food Chem. 52, 4893 (2004), Abstract
Biochemistry on postharvest metabolism and deterioration of some tropical tuberous crops: I. Uritani; Bot. Bull. Acad. Sinica 40, 177 (1999)

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