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3-Methyladenine

LSI-AC-1002

Axxora Marketplace
  • LSI-AC-1002-0050   —   50 mg
    $250.00
  • LSI-AC-1002-0100   —   100 mg
    $295.00

3-Methyladenine inhibits autophagy by blocking autophagosome formation via inhibition of type III phosphatidylinositol 3-kinases (PI-3K). It protects 1321N1 astrocytoma cells against pyocyanin and hydroxyphenazine-induced toxicity. Inhibition of autophagy by 3-MA leads to enhanced apoptosis induced by a variety of agents including celastrol, cisplatin and sorafenib in several different cell lines.

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Regulatory Status

RUO – Research Use Only