Home Shop 3-Bromo-7-nitroindazole

3-Bromo-7-nitroindazole

ALX-270-009

8 citations

Datasheet
Manual
SDS
CofA

Already have an account?

NOS inhibitor

Potent inhibitor of rat cerebellar nitric oxide synthase (nNOS/NOS I). More potent than 7-nitroindazole.

Shipping: Available products typically ship within 24/48h, via priority shipping.

Do you need support? Contact Customer Service or Technical Support.

Online Account
Access or Create Your Account

Product Details

Appearance	Yellowish solid.
CAS	74209-34-0
Couple Target	NOS
Couple Type	Inhibitor
Formula	C₇H₄BrN₃O₂
MW	242.0
Purity	≥98%
Solubility	Soluble in DMSO (50mg/ml), methanol or 100% ethanol; also soluble in water containing 10% DMSO or in a 50:50 mixture of water:DMSO.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons: Sunico, C. R., Sultan, A., et al.; PNAS 113, E7564 (2016), Abstract
S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson’s disease: Sunico, C. R., Nakamura, T., et al.; Mol. Neurodegener. 8, 29 (2013), Abstract
Effects of selective neuronal nitric oxide synthase inhibition on sleep and wakefulness in the rat: M. Cavas & J.F. Navarro; Prog. Neuropsychopharmacol. Biol. Psychiatry 30, 56 (2006), Abstract
Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism: C.S. Raman, et al.; Biochemistry 40, 13448 (2001), Abstract
3-bromo-7-nitroindazole, a neuronal nitric oxide synthase inhibitor, impairs maternal aggression and citrulline immunoreactivity in prairie voles: S.C. Gammie, et al.; Brain Res. 870, 80 (2000), Abstract
Evidence for involvement of the neuronal isoform of nitric oxide synthase during induction of long-term potentiation and long-term depression in the rat dentate gyrus in vitro: J. Wu, et al.; Neuroscience 78, 393 (1997), Abstract
Further in vivo studies on attenuating morphine withdrawal: isoform-selective nitric oxide synthase inhibitors differ in efficacy: D.B. Vaupel, et al.; Eur. J. Pharmacol. 324, 11 (1997), Abstract
7-Nitro indazole derivatives are potent inhibitors of brain, endothelium and inducible isoforms of nitric oxide synthase: P.A. Bland-Ward & P.K. Moore; Life Sci. 57, PL131 (1995), Abstract

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Datasheet

Certificate of Analysis

Please enter the lot number as featured on the product label

Lot No. :

SDS

Enzo Life Science provides GHS Compliant SDS

English (EU) SDS

If your language is not available please fill out the SDS request form

Your Cart

Your Cart

3-Bromo-7-nitroindazole

ALX-270-009

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

Manuals And Inserts

Certificate of Analysis

SDS

Change Country

Tell us about You

Tell us about your paper

Tell us about You

Tell us about your project