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A cell permeable, selective, and ATP-competitive inhibitor of Rho kinase (ROCK) activity (IC50=25µM). Does not inhibit the activation of Rho nor does it affect the in vitro activities of MLCK, PKCα, and SAPK2a/p38α. Shown to be less potent than Y-27632 (Prod. No. ALX-270-333).
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| Regulatory Status |
RUO – Research Use Only |
|---|
Related Products
| Alternative Name | (R)-(+)-trans-N-(4-Pyridyl)-4-(1-aminoethyl)-cyclohexanecarboxamide . 2HCl |
|---|---|
| CAS | 129830-38-2 |
| Couple Type | Inhibitor |
| Purity | ≥98% (HPLC (UV)) |