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24(R),25-Dihydroxyvitamin D3

BML-DM300

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Major metabolite of vitamin D3

Major metabolite of vitamin D₃. Mediates calcium and phosphorous homeostasis. Inhibits 1α,25-dihydroxyvitamin D3 and testosterone potentiation of calcium channels in osteosarcoma cells.

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Product Details

CAS	55721-11-4
Formula	C₂₇H₄₄O₃
Formulation	White solid dissolved in ethanol (50µg/50µl).
MW	416.6
Purity	≥98% (TLC)

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended. Store, as supplied, at -80°C for up to 1 year.
Long Term Storage	-80°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Effects of Topical 1,25 and 24,25 Vitamin D on Diabetic, Vitamin D Deficient and Vitamin D Receptor Knockout Mouse Corneal Wound Healing: X. Lu, et al.; Biomolecules 13, 1065 (2023), Abstract
Vitamin D receptor and metabolite effects on corneal epithelial cell gap junction proteins: Lu, X., Chen, Z., et al.; Exp. Eye Res. 187, 107776 (2019), Abstract
24R,25-(OH)2 vitamin D3 inhibits 1alpha,25-(OH)2 vitamin D3 and testosterone potentiation of calcium channels in osteosarcoma cells: K. Takeuchi, et al.; J. Biol. Chem. 271, 33335 (1996), Abstract
24R,25-Dihydroxyvitamin D3 and 1 alpha,25-dihydroxyvitamin D3 are both indispensable for calcium and phosphorus homeostasis: A. W. Norman, et al.; Life Sci. 27, 229 (1980), Abstract

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24(R),25-Dihydroxyvitamin D3

BML-DM300

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

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