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2′,2”,2”’,2””,2””’,2”””-Hexa-F-c-hexadAMP

BLG-H038

Axxora Marketplace
  • BLG-H038-001   —   0.1 µmol
    $393.00
  • BLG-H038-005   —   5x0.1 µmol

2′,2”,2”’,2””,2””’,2”””-Hexa-F-c-hexadAMP is an analogue of the bacterial second messenger c-hexaAMP (Cat. No.: BLG-C332) containing fluoro modifications in all ribose 2′-positions. 2′,2”,2”’,2””,2””’,2”””-Hexa-F-c-hexadAMP was found to be resistant to degradation by the type III CRISPR-associated ribonuclease Csm6 from Enterococcus italicus (EiCsm6) while it still activated EiCsm6 (EC50 = 170 nM), albeit more weakly than c-hexaAMP.

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Regulatory Status

RUO – Research Use Only