2′,2”,2”’,2””,2””’,2”””-Hexa-F-c-hexadAMP

2′,2”,2”’,2””,2””’,2”””-Hexa-F-c-hexadAMP is an analogue of the bacterial second messenger c-hexaAMP (Cat. No.: BLG-C332) containing fluoro modifications in all ribose 2′-positions. 2′,2”,2”’,2””,2””’,2”””-Hexa-F-c-hexadAMP was found to be resistant to degradation by the type III CRISPR-associated ribonuclease Csm6 from Enterococcus italicus (EiCsm6) while it still activated EiCsm6 (EC50 = 170 nM), albeit more weakly than c-hexaAMP.

BLG-H038-005 (5 x 0.1 µmol pack size) is not sold in the U.S. or Canada. Please contact us for available options.