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Cyclic oligoadenylates such as c-tetraAMP (Biolog Cat. No. C 335) were found to be novel bacterial second messengers involved in the Type III CRISPR-Cas-associated detection and degradation of invasive genetic elements in many prokaryotes. 2′,2”,2”’,2””-Tetra-c-tetradAMP is an analogue of c-tetraAMP containing deoxy modifications in all ribose 2′-positions, which are expected to make the compound resistant to degradation by nucleases.
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| Regulatory Status |
RUO – Research Use Only |
|---|
Related Products
2′,2”,2”’,2””-Tetra-F-c-tetradAMP
BLG-T062
Fluorinated version of the bacterial second messenger c-tetraAMP
| Alternative Name | 2′-,2”-,2”’,2””-Tetradeoxy- 2′-,2”,2”’,2””- tetrafluoro-cyclic tetraadenosine monophosphate . sodium salt, cFA4, Tetrafluoro-c-tetraAMP |
|---|---|
| Couple Type | Modified nucleotides |
| Purity | > 95% HPLC |
| Alternative Name | Cyclic tetraadenosine monophosphate . sodium salt, Cyclic tetraadenylate, c-A4 |
|---|---|
| Purity | > 95% HPLC |
2′,2”,2”’,2””-Tetra-O-Me-c-tetraAMP
BLG-T066
Analogue of c-tetraAMP containing O-methyl modifications in all ribose 2′-positions
| Alternative Name | 2′-, 2”, 2”’, 2””-Tetra-O-methyl-cyclic tetraadenosine monophosphate . sodium salt |
|---|---|
| Couple Type | Modified nucleotides |
| Purity | > 95% HPLC |