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21-Hydroxyoligomycin A

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Antitumor antibiotic

Co-metabolite of nemadectin. Antitumor agent with weak antifungal and nematocidal activity.

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Alternative Name	Nemadectin ω, Antibiotic LL-F28249 ω
Appearance	White to off-white powder.
CAS	102042-09-1
Formula	C₄₅H₇₄O₁₂
MW	807.1
Purity	≥95% (HPLC)
Solubility	Soluble in 100% ethanol, methanol, dimethyl formamide or DMSO.
Source	Isolated from Streptomyces sp. AS5351.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Structure and absolute stereochemistry of 21-hydroxyoligomycin A: M.M. Wagenaar, et al.; J. Nat. Prod. 70, 367 (2007), Abstract
Plasmid effects on secondary metabolite production by a streptomycete synthesizing an anthelmintic macrolide: D.I. Thomas, et al.; J. Gen. Microbiol. 137, 2331 (1991), Abstract

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