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20-Hydroxyecdysone

ALX-370-012

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ALX-370-012-M005 — 5 mg

$87.00

20-Hydroxyecdysone quantity
ALX-370-012-M010 — 10 mg

$155.00

20-Hydroxyecdysone quantity
ALX-370-012-M050 — 50 mg

$602.00

20-Hydroxyecdysone quantity

Ecdysteroid

Most widely occurring ecdysteroid in both plant and animal species. Controls cell death during metamorphosis of Drosophila melanogaster.

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Product Details

Alternative Name	β-Ecdysone, 2β,3β,14α,20R,22R,25-Hexahydroxy-5β-cholest-7-en-6-one, Ecdysterone
Appearance	White powder.
CAS	5289-74-7
Formula	C₂₇H₄₄O₇
MI	14: 3491
MW	480.6
Purity	≥95% HPLC
Solubility	Soluble in water, 100% ethanol, methanol, DMSO and acetic acid.

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Nuclear position and local acetyl-CoA production regulate chromatin state: P. Willnow, et al.; Nature 630, 466 (2024), Abstract
Mating-Induced Increase in Germline Stem Cells via the Neuroendocrine System in Female Drosophila: T. Ameku, et al.; PLoS One 12, e1006123 (2016), Application(s): Ecdysteroid level measurement standard, Abstract — Full Text
Arthropod steroid hormone (20-Hydroxyecdysone) suppresses IL-1β- induced catabolic gene expression in cartilage: S.Y. Sheu, et al.; BMC Complement. Altern. Med. 15, 1 (2015), Application(s): Cell Culture, Abstract — Full Text
Regulation of Pattern Formation and Gene Amplification During Drosophila Oogenesis by the miR-318 microRNA: W. Ge, et al.; Genetics 200, 255 (2015), Application(s): Cell Culture, Abstract — Full Text
The silkworm glutathione S-transferase gene noppera-bo is required for ecdysteroid biosynthesis and larval development: S. Enya, et al.; Insect Biochem. Mol. Biol. 61, 1 (2015), Application(s): Functional Studies (used as standard), Abstract
Fork head controls the timing and tissue selectivity of steroid-induced developmental cell death: C. Cao, et al.; J. Cell Biol. 176, 843 (2007), Abstract
A novel method of isolation of phytoecdysones from kaladana seeds: L. Canonica, et al.; Phytochemistry 14, 525 (1975)
Vorkommen von 20-Hydroxy-ecdyson in Vitex megapotamica: H. Rimpler & G. Schulz; Tetrahedron Lett. 22, 2033 (1967), (Article in German)
Structure of crustecdysone, a crustacean moulting hormone: H. Hampshire & D.H.S. Horn; Chem. Commun. (London) 1966, 37 (1966), Abstract
An insect-moulting hormone from a plant: M.N. Galbraith & D.H.S. Horn; Chem. Commun. (London) 1966, 905 (1966), Abstract