Home Shop 2-Thio(3-iodobenzyl)-5-(1-pyridyl)-[1,3,4]-oxadiazole

2-Thio(3-iodobenzyl)-5-(1-pyridyl)-[1,3,4]-oxadiazole

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GSK-3β inhibitor

Potent inhibitor of glycogen synthase kinase-3β (GSK-3β) (IC₅₀=390nM).

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Alternative Name	TIBPO
Appearance	Yellow solid.
CAS	478482-75-6
Couple Target	GSK
Couple Type	Inhibitor
Formula	C₁₄H₁₀IN₃OS
Formulation	Lyophilized.
MW	395.2
Purity	≥95% (HPLC)
Solubility	Soluble in DMSO (10mg/ml) or 100% ethanol.

Use/Stability	As indicated on product label or CoA when stored as recommended.
Handling	Protect from light and moisture. Keep under inert gas.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors: L. Naerum, et al.; Bioorg. Med. Chem. Lett. 12, 1525 (2002), Abstract

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