14-3-3ζ (human), (recombinant) (His-tag)

14-3-3 proteins are dimeric phosphoserine/phosphothreonine binding proteins, which have been shown to be involved in the regulation of many crucial processes such as signal transduction, cell-cycle control, apoptosis, protein localization, phosphorylation state and stability, transcription, metabolism, and malignant transformation. 14-3-3ζ has been shown to be present in brain amyloid plaques. It has also been hypothesized that 14-3-3ζ is recruited by cells to form protein aggregates with misfolded proteins in order to protect the cell against toxicity.