14-3-3θ/τ (human), (recombinant) (His-tag)

14-3-3 proteins are dimeric phosphoserine/phosphothreonine binding proteins, which have been shown to be involved in the regulation of many crucial processes such as signal transduction, cell-cycle control, apoptosis, protein localization, phosphorylation state and stability, transcription, metabolism, and malignant transformation. 14-3-3θ/t has been shown to be present in testis and 14-3-3θ mRNA is up-regulated in amyotrophic lateral sclerosis spinal cord. Both PKCµ and Bax have been shown to be negatively regulated by 14-3-3θ