[13C20,15N10]-c[G(2′,5′)pA(3′,5′)p] / [13C20,15N10]-2’3′-cGAMP
BLG-C410
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[13C20,15N10]-c[G(2′,5′)pA(3′,5′)p] is the stable isotope version of the metazoan cyclic dinucleotide second messenger c[G(2′,5′)pA(3′,5′)p] / 2’3′-cGAMP (Biolog Cat. No. C 161). c[G(2′,5′)pA(3′,5′)p] is produced by the mammalian innate immune DNA sensor cGAMP synthase (cGAS) and potently activates the immune signalling protein STING (stimulator of interferon genes). [13C20,15N10]-c[G(2′,5′)pA(3′,5′)p] is suitable as internal standard in LC-MS applications for c[G(2′,5′)pA(3′,5′)p]. The isotopic purity is 98% for 13C and 15N, respectively.
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