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13-cis-Retinoic acid

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Retinoic acid receptor ligand

A potent modulator of growth and differentiation. Clinically used in a variety of skin disorders.

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Alternative Name	Isotretinoin
Appearance	Orange solid.
CAS	4759-48-2
Couple Target	Retinoic acid receptor
Couple Type	Ligand
Formula	C₂₀H₂₈O₂
MW	300.4
Purity	≥95% (TLC)
Solubility	Soluble in DMSO (25mg/ml) or ethanol (25mg/ml).

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Blue Ice

Regulatory Status	RUO – Research Use Only

Pharmacological effects of retinoids on skin cells: G.J. Gendimenico & J.A. Mezick; Skin Pharmacol. 6, Suppl. 1, 24 (1993), Abstract
Clinical pharmacology of 3 generations of retinoids: A. Vahlquist, et al.; Dermatologica 175 Suppl. 1, 20 (1987), Abstract

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