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11-dehydro-TXB2 ELISA kit

ADI-900-092

10 citations

ELISA kit
  • ADI-900-092   —   96 wells
    $479.00
  • Higher throughput – measure up to 38 samples in duplicate in just 3 hours
  • Easy-to-use – works with any standard colorimetric plate reader, no specialized training required
  • Ready-to-use liquid color-coded reagents save time and reduce errors
  • More sensitive than other commercially available kits
  • Specific – low reactivity to structurally related molecules

The 11-dehydro-TXB2 EIA kit is a colorimetric competitive enzyme immunoassay kit with results in 3 hours. Absorbance is read at 405 nm. This kit offers ultrasensitive quantification of 11-d-TXB2 in a variety of sample matrices with negligible reactivity with related molecules in a convenient 96-well format offers higher throughput analysis compared to conventional analytical methods.

Thromboxane A2 (TXA2) is involved in platelet aggregation, vasoconstriction and reproductive functions, but has a half life of only 37 seconds under physiological conditions. Thromboxane B2 (TXB2) is the stable product of the non-enzymatic hydration of TXA2, thus the production of TXA2 in vivo is typically monitored by measurement of TXB2 and its metabolite 2,3-dinor TXB2. 11-dehydro-TXB2 is a major metabolite of Thromboxane B2 (TXB2) found in urine and plasma produced by its dehydrogenation by the enzyme 11-OH-dehydrogenase.

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Regulatory Status

RUO – Research Use Only