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β-Amyloid (1-42)

ALX-151-002

10 citations

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Product Details

Appearance	White to off-white lyophilized powder.
CAS	107761-42-2
Formula	C₂₀₃H₃₁₁N₅₅O₆₀S
MW	4514.1
Purity	≥95% (HPLC)
Quantity	*Sold as net peptide weight.
Sequence	H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-OH
Solubility	Soluble in 5% acetic acid.
Technical Info / Product Notes	Application Note: Analysis of the Effect of Aggregated β-Amyloid on Cellular Signaling Pathways Critical for Memory in Alzheimer’s disease

Handling & Storage

Use/Stability	As indicated on product label or CoA when stored as recommended.
Long Term Storage	-20°C
Shipping	Ambient Temperature

Regulatory Status	RUO – Research Use Only

Exploring the therapeutic efficacy of Chlorella pyrenoidosa peptides in ameliorating Alzheimer’s disease: S.M. Wang, et al.; Heliyon 9, e15406 (2023), Abstract
Clausena Harmandiana root extract attenuated cognitive impairments via reducing amyloid accumulation and neuroinflammation in Aβ1-42-induced rats: N. Nillert, et al.; BMC Complement Med. Ther. 22, 108 (2022), Abstract
Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease: L. Gallwitz, et al.; Neurobiol. Dis. 175, 105919 (2022), Abstract
Amyloid and Tau Induce Cell Death Independently of TSPO Polymerization and Density Changes: Tournier, B. B., Ceyzériat, K., et al.; ACS Omega 6, 18719 (2021), Abstract
Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models: M.C. Silva, et al.; Elife 8, e45457 (2019), Abstract — Full Text
Heptamer Peptide Disassembles Native Amyloid in Human Plasma Through Heat Shock Protein 70: T.J. Cunningham, et al.; Rejuvenation Res. 21, 527 (2018), Abstract
Solution structures of beta peptide and its constituent fragments: relation to amyloid deposition: C.J. Barrow & M.G. Zagorski; Science 253, 179 (1991), Abstract
A mutation in the amyloid precursor protein associated with hereditary Alzheimer’s disease: J. Murrell, et al.; Science 254, 97 (1991), Abstract
The precursor of Alzheimer’s disease amyloid A4 protein resembles a cell-surface receptor: J. Kang, et al.; Nature 325, 733 (1987), Abstract
Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer’s disease: D. Goldgaber, et al.; Science 235, 877 (1987), Abstract

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β-Amyloid (1-42)

ALX-151-002

Product Details

Handling & Storage

Datasheet, Manuals, SDS & CofA

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