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Technotes
How To Determine Protein Stability
Why is it important to understand protein stability? Protein stability is a major concern for biotechnology, food industries, pharmaceuticals, and…
Mon, Jan 30, 2023
Cell-Based Assay or Biochemical Assay? Now That’s the Question…
Cell-based and biochemical assays provide end users with valuable tools for drug discovery applications and high throughput screening. Cell-based assays,…
Mon, Jan 30, 2023
How to Validate Sample Dilutions and Achieve Linearity in New Sample Types
Immunoassay Sample Validation Experiments – What is Matrix Interference? Enzyme-linked immunosorbent assay (ELISA) is a microplate-based technique frequently used for…
Mon, Jan 30, 2023
How Do Histone Modifications Regulate Gene Expression?
Eukaryotic DNA is packaged and wrapped around proteins known as histones which protect and regulate gene expression. The structure of…
Mon, Jan 30, 2023
What are the Pros and Cons of FISH, aCGH and NGS?
To understand the role that chromosomal variations play in disease, cytogenetic analysis has become an integral part of current medicine.…
Mon, Jan 30, 2023
What are the different methods of determining protein aggregation?
What is protein aggregation and what factors influence protein aggregation? Protein aggregation is undesired interaction between protein monomers and can…
Mon, Jan 30, 2023
How do you choose the right fluorophore?
Fluorescence detection is a highly sensitive technique widely used in biotechnology, flow cytometry, medical diagnostics, DNA sequencing, forensics, and genetic…
Mon, Jan 30, 2023
Irisin: A Fat Fighting Exercise Hormone
Cardiovascular diseases (CVDs) including myocardial infarction and strokes are consistently ranked as the largest cause of death in the world.…
Mon, Jan 30, 2023
What are the differences between Northern, Southern and Western Blotting?
Different blots are used to identify the presence of one specific target molecule (DNA, RNA or protein) in a complex…
Fri, Jan 27, 2023
What are the different detection methods for IHC?
Immunohistochemistry (IHC) is a powerful and routinely used technique for the detection, localization, and scoring of cellular macromolecules in preserved…
Fri, Jan 27, 2023