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Technotes
Why Study Cell Viability, Cell Proliferation and Cytotoxicity?
Cell-based assays are the main stay in drug discovery projects, where collections of compounds are screened to assess effects on…
Mon, Feb 06, 2023
What is the difference between Th1- and Th2- T cells?
Lymphocytes T (or T cells) are key mediators of adaptive immunity, the part of the immune system capable of generating…
Mon, Feb 06, 2023
Tools to study adaptive and innate immune response
Basics of Immunity Even though the most sophisticated immunity mechanisms are those of vertebrates, some sort of innate defense is…
Mon, Feb 06, 2023
Drug toxicity screening using induced pluripotent stem cells and high-content analysis
Toxicity, and more specifically hepatotoxicity, is a major concern for the pharmaceutical industry. Both drug candidates and approved drugs face…
Mon, Feb 06, 2023
Can You Regrow Your Brain?
It is upon us – the zombie apocalypse. Some greedy corporation has tinkered with things they should have left untouched,…
Mon, Feb 06, 2023
What is in situ hybridization and what are the recent advancements with this indispensable technique?
In situ hybridization (ISH) is a widely used method to localize and quantify DNA or RNA in cytological preparations (metaphase…
Mon, Feb 06, 2023
Cardiotoxic drugs and mechanisms of cardiotoxicity
The discovery of penicillin changed the course of medicine and it is, probably for this very reason, one of the…
Mon, Feb 06, 2023
Targeting Biomarkers for Tissue-Agnostic Therapies for Cancer Treatment
Cancer Defined The human body begins as a single zygotic cell, which grows, proliferates, and differentiates into a collection of…
Mon, Feb 06, 2023
Drugging the “Undruggable” genes
In the long, laborious (and expensive) path of drug discovery, finding the right target to develop a treatment is the…
Mon, Feb 06, 2023
IHC Counterstains for Enzyme/Chromogen and Fluorescent Immunostaining
What is a Counterstain? A counterstain is a stain or dye that has a color contrasting to the first or…
Mon, Feb 06, 2023