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There has been significant interest in the role of programmed cell death protein 1 (PD-1) and its ligand programmed death-ligand 1 (PD-L1) in modulating immune responses. The emergence of PD-1-targeted therapies has revolutionized cancer treatment, leading to a better understanding of immune checkpoint mechanisms and their uses in various research fields.
This paper offers a review of significant publications on the use of PD-1 antibodies in cancer, immunology, and Alzheimer’s disease research. We will highlight the importance of PD-1 antibodies in resolving the complicated interactions between the immune system and pathological conditions as well as their potential to create novel therapeutic approaches.
