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With apoptosis being a widely investigated research field, many technologies have emerged to study programed cell death. ImmunoChemistry Technologies is focusing on non-cytotoxic fluorescent labeled inhibitors of caspases that covalently bind to active caspase enzymes. Their FLICA® probes measure the intracellular process of apoptosis instead of a side-effect, such as the turnover of phosphatidyl serine, and eliminates the incidence of false positives that often plagues methods like Annexin V and TUNEL staining.
