My stock solution was initially clear, but when I removed it from the freezer to use it a second time, a precipitate formed. What should I do?

Date Published: July 18, 2023

The process of a solution freezing and thawing can sometimes cause chemicals to crystallize or precipitate out of solution. This is most common in solutions at concentration near the upper limit of solubility. These precipitates are temporary, and will normally redissolve on their own as the solution warms up to room temperature. If the precipitate is slow to redissolve, a few minutes of warming in a 37°C water bath with sonication will normally solve the problem.

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