No, these are colorimetric ELISA kits for the quantification of extra-cellular cAMP/cGMP in culture supernatants, serum, and saliva from any species. For intra-cellular cAMP/cGMP, Enzo Life Sciences offers specifically dedicated Direct ELISA kits: ADI-900-066A for cAMP and ADI-900-014 for cGMP. If you would like to measure both intra- and extra-cellular cAMP/cGMP concentrations, our complete ELISA kits would be the best choice: ADI-900-163A for cAMP and ADI-900-164 for cGMP.