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Target Identification

Increase the Odds of Finding a New Drug

Find Better Targets for Drug Development

Target identification is a crucial step in the drug discovery process, which aims to identify a biological target for a specific disease or condition. This involves the identification of specific proteins or enzymes that are involved in the disease process and are essential for its progression.

Various methods are utilized for target identification, including genetic, biochemical, and phenotypic approaches. Genetic techniques like GWAS and gene expression analysis unveil disease-associated genes or mutations, shedding light on underlying biological pathways. Biochemical approaches involve the use of assays to identify proteins or enzymes that are involved in the disease process. Phenotypic screening involves the use of cellular or organismal models and is particularly valuable for complex diseases where the underlying molecular mechanisms are poorly understood or involve multiple interacting targets.

Enzo Offers Multiple Solutions to Identify Potential Targets for Drug Development

AMPIVIEW® RNA Probes

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To address the challenges of target identification and gene expression in Drug Discovery, the AMPIVIEW® RNA probes, powered by Enzo’s LoopRNA™ ISH technology, provide visualization of the spatial localization of target genes in their tissue context without disrupting cell morphology.

AMPIVIEW® EGFR (AS) Dig RNA Probes Set

To address the challenges of target identification and gene expression in Drug Discovery, the AMPIVIEW® RNA probes, powered by Enzo’s LoopRNA ISH™ technology, provide visualization of the spatial localization of target genes in their tissue context without disrupting cell morphology.

Detection of unique nucleic acid targets (DNA/RNA or RNA) down to a single cell level
Simple protocols of 2-hour hybridization and one-step amplification
Adaptable products ready for any workflow (Manual or Automated)

Product Information

AMPIVIEW® RNA Probes Deliver Superior Sensitivity and Specificity

AMPIVIEW® RNA probe s workflow diagram. Detection of epidermal growth factor receptor (EGFR) in prostate tissue with A. AMPIVIEW® EGFR (AS) Dig RNA probes and B. AMPIVIEW® NSP Dig RNA probes, amplified with DIGX® anti-digoxigenin, detected with POLYVIEW® PLUS AP combined with HIGHDEF® Red AP chromogen and hematoxylin.

Antibodies

High Quality Antibodies Delivering Superior Results

Enzo Life Sciences offers thousands of antibodies against peptides, whole or partial proteins, and modified peptides or proteins. Backed by thousands of peer-reviewed citations, our Worry-Free Guarantee, and expert technical support, you can count on Enzo antibodies to deliver reliable, consistent, accurate data.

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Rigorously validated for WB, IP, ELISA, IHC, ICC, IF, and flow cytometry
Superb performance documented in thousands of peer-reviewed publications
Expanded utility provided by common fluorophore and enzyme conjugates
Bulk production and custom conjugation/formulation services to meet your needs

Small Molecules

One of the primary applications of small molecules in drug discovery is target identification. Identifying the target of a small molecule is a crucial step in understanding its mechanism of action, which can guide further drug development efforts. Enzo Life Sciences has a long and successful track record in identifying, synthesizing, and commercializing valuable known bioactives for use as research tools.

Choose from Over 3,000 Compounds

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Natural Products
Enzyme inhibitors
Receptor Ligands
Drugs

Drug Repurposing Libraries

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Drug repurposing is a strategy that involves identifying new therapeutic uses for existing drugs. Drug repurposing libraries are collections of existing drugs that have been approved for use in humans. These libraries are typically composed of hundreds or thousands of compounds, and they are often screened against various diseases to identify potential new therapeutic uses. Drug repurposing libraries offer a cost-effective and time-efficient approach to identifying new therapeutic uses for existing drugs, and have the potential to provide new treatments for diseases where there are currently no effective therapies.

SCREEN-WELL® FDA Approved Drug Library V2

Accelerate drug optimization with a unique collection of compounds of known safety and bioavailability for diverse targets

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Compounds can be used for diverse drug discovery in the fields of cardiology, neuropsychiatry, immunology, oncology and more!
Contains more than 100 additional compounds compared to our previous FDA approved library versions 100% known bioactivity and greatest degree of druglikeness available.Recently approved FDA compounds are also included We provide detailed information in our comprehensive documentation for each compound

Drug Discovery Kits

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Drug discovery kits are essential tools for identifying potential targets for new drug development. Targets are typically biomolecules such as proteins, enzymes, or receptors that are involved in the disease pathology. Identifying these targets can provide insights into the underlying molecular mechanisms of the disease and enable the development of new therapeutic strategies.

MMP RED and GREEN Drug Discovery Kits

Improved red-shifted substrate with better kinetics and brighter signal
Includes active recombinant enzyme, substrate, and assay buffer
Convenient real-time kinetics of cleavage is easily determined
Microplate format for high-throughput screening

Featured Solutions for Target Identification

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Target Identification

Find Better Targets for Drug Development

Enzo Offers Multiple Solutions to Identify Potential Targets for Drug Development

AMPIVIEW® RNA Probes

AMPIVIEW® EGFR (AS) Dig RNA Probes Set

AMPIVIEW® RNA Probes Deliver Superior Sensitivity and Specificity

Antibodies

High Quality Antibodies Delivering Superior Results

Small Molecules

Choose from Over 3,000 Compounds

Drug Repurposing Libraries

SCREEN-WELL® FDA Approved Drug Library V2

Accelerate drug optimization with a unique collection of compounds of known safety and bioavailability for diverse targets

Drug Discovery Kits

MMP RED and GREEN Drug Discovery Kits

Featured Solutions for Target Identification

Choose from Over 3,000 Compounds

FDA Approved Compound Library

MMP Drug Discovery Assays

Comprehensive Tools for Epigenetic Modification

Latest Articles

How Are New Drugs Discovered and What Are Some of the Current Challenges in Drug Development?

Drug Discovery

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