Vaccines

Creating Efficiency & Maintaining Quality to Accelerate Your Vaccine Manufacturing

Vaccines are a crucial tool used in public health to control the spread of infectious diseases. Historically, vaccines have been the single most effective means to fight and ultimately eradicate certain infectious diseases. Today, vaccines are in high demand as the global community struggles through epidemics of diseases that do not yet have a vaccine. We provide reagents to ensure that your vaccines are first-to-market and cost-effective, two key issues that can make or break the launch of a vaccine. As part of our portfolio, we offer tools to develop cell-based cancer vaccines, which efficiently target heterogenous cancer cells. Enzo Life Sciences offers a comprehensive offering of tools and forty years of expertise to ensure that your development is successful, from target identification to launch.

High-quality vaccine research and manufacturing products that consistently yield reproducible results, ensuring efficiency in time, effort and cost reduction in every lot.

Native Bacterial and Viral Antigens

  • Higher specificity and sensitivity
  • Reproducible scale-up and lot-to-lot consistency
  • Lyophilized format for extended shelf-life
Pertussis Toxin
A model is built using data of molecular structure from CPs Undetected HCPs Protein Data Bank (PDB 1PRT)

HCP ELISAs

  • Sensitive measurement of host cell protein, detecting as little as 10 ng/ml
  • High protein coverage greater than 70% thereby, reducing the risk of missing potential contaminants
  • High-throughput format with results in as little as 3 hours

Related Products
CHO HCP Standards
CHO HCP polyclonal antibody
CHO HCP polyclonal antibody (biotin conj)
E.coli HCP Standards
E.coli HCP polyclonal antibody
E.coli HCP polyclonal antibody (biotin conj)
HEK293T Host Cell Protein Standard

Monitor CHO HCP Residuals with Confidence
CHO Host Cell ELISA Protein Kit was compared to the leading competitor’s kit. Results indicate that Enzo’s ELISA kit has 25% more coverage than the leading competitor’s kit

MEGACD40L® Protein (soluble)(human)(recombinant)

  • Optimized formulation for improved stability and enhanced activity
  • Superior purity and low endotoxin levels eliminate experimental artifacts
  • Reliable and consistent lot-to-lot performance

Related Products
Monophosphoryl Lipid A (synthetic)
MALP-2
Polyinosinic-polycytidylic acid . potassium salt (TLRGRADE®) (synthetic)
Paclitaxel
R-848
ODN 2006 (TLRGRADE®) (synthetic)
ODN 1826 (TLRGRADE®) (synthetic)

Improved Stability and Enhanced Activity Compared to CD40L and CD40L with enhancers
B cell lymphocyte activation by various CD40L constructs. PBMCs were treated for 48 hours in media containing serially diluted CD40L, CD40L + 2 μg/mL Enhancer, or MEGACD40L® Protein. Cells were dual-stained with α-human CD19–PE and α-human CD86–APC and analyzed by flow cytometry. Data are presented as the percent of CD19+ B cells that co-stain as CD86+.

PROTEOSTAT® Protein Aggregation Assay

  • Monitor bulk freezing and freeze/thaw cycle-induced aggregation and define post-purification storage conditions
  • Identify inhibitors of protein aggregation
  • Rank effectiveness of buffers and excipients in protein formulations

Related Products
PROTEOSTAT® Protein Aggregation Standards
PROTEOSTAT® Protein Refolding and Aggregation sensing kit
PROTEOSTAT® Thermal Shift Stabillity Assay Kit
PROTEOSTAT® Aggresome Assay

PROTEOSTAT® Dye Yields Much Brighter Signal
Signal intensity of PROTEOSTAT® aggregate sensing dye compared other dyes

IL-6 (Human), High Sensitivity ELISA Kit

  • High sensitivity (0.057 pg/mL) colorimetric immunoassay kit available able to detect very low concentrations of IL-6
  • Highly specific, showing minimal crossreactivity to IL-1, IL-1αβ, IL-2, IL-3, IL-4, IL-7, IL-8, TNFα, and TNFβ
  • Validated with several sample types: plasma, serum, culture supernatants, and urine

Related Products
IFN-γ (human), ELISA kit
IL-8 (human), ELISA kit
IL-1β (human), ELISA kit
TNF-α (human), ELISA kit
IL-10 (human), ELISA kit
cAMP complete ELISA kit
PGE2 high sensitivity ELISA kit

Detect IL-6 in Several Sample Types
Parallelism curve for IL-6 (human), high sensitivity ELISA kit

Antibodies

Antibodies are indispensable tools in vaccine research, from initial antigen discovery to vaccine design, efficacy testing, manufacturing, and quality control. They are fundamental in understanding and harnessing the immune response to develop safe and effective vaccines.



Featured CD Marker Antibodies: CD3, CD4, CD8, CD40, CD20, CD19, MHC Class I.

LAG-3 (human) recombinant monoclonal antibody (L4-PL33)

LAG-3 is used as a marker in immune monitoring and assessment of vaccine-induced immune responses. Measuring LAG-3 expression on T cells provides insights into the immune system’s status and its potential to respond to vaccination.

  • A broad range of antibodies for use in all areas of vaccine research
  • Validated for use in key applications such as flow cytometry, immunohistochemistry, immunoprecipitation, and Western blotting
  • Backed by our Worry-Free Guarantee.
Detection of LAG-3 in Human Tonsil Tissue
Immunohistochemistry analysis of human tonsil tissue (60x) using LAG-3 (human) recombinant mAb (L4-PL33), at a dilution of 1:50

Enabling Vaccine Research & Manufacturing

Leverage over 45 years of innovation and technical expertise supporting drug development, discovery, research, and diagnostics through our core technology platforms. With over 150,000 citations, GMP and ISO certifications, our highly-sensitive, quality products consistently deliver trusted results. We maintain product integrity and reliability with our in-house U.S. manufacturing facility. We deploy our bench of expert PhD scientists to provide technical, tailored, support for our customers and their projects.

Rely on our extensive experience in innovation, technology development, and manufacturing to support your vaccine research and development. Our comprehensive Life Sciences Contract Services support the development of customizable, unique, and efficient solutions for all your research needs.

Our Technological Depth Enabling Efficiency for our Customers.


Latest Articles


Vaccine

Download Resource