Cell Death, Apoptosis, or Necrosis

Visualize Toxic Events In Vitro

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How to Detect Key Features of Apoptosis?

Apoptosis, or programmed cell death, is naturally occurring and activated by caspases that cleave proteins. Caspases are classified as effector or initiator caspases and can be used to determine apoptosis. Necrosis is an alternative to apoptosis and is not a regulated process. Injury, diseases, or external factors results in premature cell death that triggers necrosis. Apoptosis and necrosis can be differentiated by evaluating caspase 3/7 pathway activation

Product Highlight

GFP-CERTIFIED® Apoptosis/Necrosis detection kit

GFP-compatible multiplex assay for distinguishing between healthy, early apoptotic, late apoptotic, and necrotic cells

  • True multiplexing capabilities with GFP and other fluorescent probes (blue and cyan)
  • Optimized for both fluorescence microscopy and flow cytometry applications
  • Suitable for death pathway analysis and drug/toxin studies
Product Information
Dual Detection of Apoptotic and Necrotic Cells
Apoptosis Detection Reagent (Gold) and Necrosis Detection Reagent (Red) specifically detect cell state with clear spectral separation from mitochondria-associated GFP signal (Green).

Predictive Toxicology

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More Apoptosis Solutions

APO-BRDU™ kit

ALX-850-042

TUNEL assay for the detection of apoptosis by flow cytometry

4 citations

Application Flow Cytometry

GFP-CERTIFIED® Apoptosis/Necrosis Detection kit

ENZ-51002

Multiplex assay that distinguishes between healthy, early apoptotic, late apoptotic and necrotic cells, compatible with GFP and other fluorescent probes (blue or cyan)

84 citations

Application Flow Cytometry, Fluorescence microscopy, Fluorescent detection

ApoSENSOR™ Cell viability assay kit

ALX-850-247

A simple no-wash, chemiluminescent cell  viability assay

Application Chemiluminescence

Calcein AM (ultra pure)

ENZ-52002

Calcium dye

7 citations

Purity ≥95% (HPLC)