BIO-PROBE® Virus Detection Assays

BIO-PROBE® Probes for sensitive detection of infectious viral DNA from fresh or FFPE tissue sections
BIO-PROBE® probes are ready-to-use biotinylated probes for ISH detection against infectious diseases viral targets including Adenovirus, Blur-8, and CMV among others.
Virus detection assays for use in a variety of hybridization techniques, including in situ hybridization at low concentrations (50-100 ng/mL). Biotinylated probes have been shown to hybridize to homologous DNA at the same rate and to the same extent as non-biotinylated probes.
Results with the Enzo probe were so good that we did not continue trying to optimize with a different probe.
Momin T. Siddiqui, MD, Department of Pathology and Laboratory Medicine, Emory University Hospital
(excerpt from Appl Immunohistochem Mol Morphol 2014; 22: 619–622)
References
- Brown DR, et. al. Neutralization of human papillomavirus type 11 (HPV-11) by serum from women vaccinated with yeast-derived HPV-11 L1 virus-like particles: correlation with competitive radioimmunoassay titer.J Infect Dis. 2001 Nov 1;184(9):1183-6.
- Lajer CB, et. al. Different miRNA signatures of oral and pharyngeal squamous cell carcinomas: a prospective translational study. Br J Cancer. 2011 Mar 1;104(5):830-40.
- Nuovo GJ, et. al. Strong inverse correlation between microRNA-125b and human papillomavirus DNA in productive infection. Diagn Mol Pathol. 2010 Sep;19(3):135-43.