Organelle Detection

Monitor subcellular organelle morphology in living cells by multiple applications

Organelles are vital cellular compartments that support the cell physiological functions: intracellular protein degradation, lipid metabolism, ATP synthesis, protein post-translational modification and transmission of DNA in dividing daughter cells. Damaged or compromised organelles are often associated with the onset and progression of a variety of diseases, including cardiovascular, neurodegenerative, cancer, autoimmune and metabolic conditions.

Organelle–targeting probes are useful as counter-stains to aid in identifying cellular constituents, co-localizing specific proteins and targets of interest, and monitoring morphological responses to chemical and environmental stresses.

Enzo comprehensive panel of fluorescence-based assays, highlighting various structural features of different subcellular organelles, offers the prospect of identifying subtle in vitro responses that could serve as predictive surrogates for in vivo toxicity testing.