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Posttranslational Modifications (PTMs)
Complete Tools to Characterize Protein Folding
Structural Characterization of Proteins
Protein synthesis, folding, and post-translational modifications (PTMs) are of vital importance in proteomic studies of biological systems. Evaluation of protein homeostasis (proteostasis) extends beyond translation, and involves assisted folding by molecular chaperones and chemical modifications to achieve a protein’s native conformation. Furthermore, a multitude of chemical modifications (e.g. phosphorylation, ubiquitinylation, acetylation, glycosylation, SUMOylation, and methylation) are utilized to regulate proper localization and function. Enzo’s extensive range of chaperone and post-translational modification reagents facilitates detailed characterization of these mechanisms of proteostasis.
Histone Post-translational Modifications
Solutions For Screening Epigenetic Regulators
For decades, the FLUOR DE LYS® deacetylase assay platform has freed researchers from cumbersome protocols for screening HDAC & Sirtuin activity. Our high-quality chemiluminescent, fluorescent, and colorimetric assays deliver more high-quality hits, and are backed by a broad panel of characterized inhibitors and PTM-specific antibodies for ubiquitinylation, sumoylation, methylation, acetylation, and phosphorylation.
Active Enzymes & Drug Discovery Assays
Convenient screening formats, featuring FLUOR DE LYS® HDAC & Sirtuin assays, transferase & demethylase assays, and high-activity enzymes.
Small Molecules & Compound Libraries
Benchmark against known epigenetic modulators.
PTM-specific Antibodies
Detect acetylation, methylation, ubiquitinylation and more with high-quality antibodies backed by our Worry-Free Guarantee.
Ubiquitin & UBL Signaling
Solutions for Screening Epigenetic Regulators
Browse hundreds of high-quality research products, including proteins and antibodies, for activating enzymes (E1s), conjugating enzymes (E2s), ligases (E3s) and deconjugating enzymes (DCEs), plus an innovative range of ubiquitin-, SUMO-, NEDD8-, ISG15- and FAT10-associated proteins and derivatives. Discover ubiquitin- and Ubl-reactive antibodies, kits for the study of ubiquitin, SUMO, and NEDD8 conjugation, and our easy-to-use UBIQAPTURE® and SUMO-QAPTURE® kits for the detection and isolation of ubiquitinylated and SUMOylated proteins.