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Epigenetics
Comprehensive Tools for Epigenetic Modification
Rapid Extraction Kits for Epigenetic Workflows
Guarantee reproducible, high-yield isolation of histones, nuclear proteins, and DNA
- Rapid, reliable methods to isolate samples to for downstream applications.
- Available in different formats with additional features to fit application.
Solutions For Screening Epigenetic Regulators
For over decades, the FLUOR DE LYS® deacetylase assay platform has freed researchers from cumbersome protocols for screening HDAC & Sirtuin activity. Our high-quality chemiluminescent, fluorescent, and colorimetric assays deliver more high-quality hits, and are backed by a broad panel of characterized inhibitors and PTM-specific antibodies for ubiquitinylation, sumoylation, methylation, acetylation, and phosphorylation.
Active Enzymes & Drug Discovery Assays
Convenient screening formats, featuring FLUOR DE LYS® HDAC & Sirtuin assays, transferase & demethylase assays, and high-activity enzymes.
Small Molecules & Compound Libraries
Benchmark against known epigenetic modulators.
PTM-specific Antibodies
Detect acetylation, methylation, ubiquitinylation and more with high-quality antibodies backed by our Worry-Free Guarantee.
Ubiquitin & Ubl Signaling
Browse our industry-leading portfolio of active enzymes, antibodies, and kits for ubiquitinylation and SUMOylation.
Convenient Kits for Sample Conversion and Detection
DNA methylation can alter gene expression, cell differentiation, and often results in unidirectional changes to genomic DNA. Its involvement in so many cellular processes means errors resulting in abnormal DNA methylation patterns can lead to disease. Expanding our expertise in epigenetic modification analysis, Enzo now offers a portfolio of products that enable detection of DNA methylation.
Sample conversion
5-mC and 5-hmC Conversion
High-efficiency conversion of 5-mC and 5-hmC DNA for the .truest downstream analysis
DNA Methylation
Detection
ELISA-Based Detection
5-Methylcytosine DNA ELISA kit
Colorimetric Assay Based Detection
DNMT Colorimetric Drug Discovery Kit
Rapid, sensitive, and simple colorimetric DNMT activity/inhibition kit.
Epigenetics
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| Alternative Name | EGCG, (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate) |
|---|---|
| CAS | 989-51-5 |
| Couple Type | Inhibitor |
| Purity | ≥98% (HPLC) |
| Alternative Name | Azacitidine, 5-AzaC, Ladakamycin, 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one |
|---|---|
| CAS | 320-67-2 |
| Purity | ≥98% (TLC) |
5-Hydroxymethylcytosine DNA ELISA kit
ADI-900-225
Highly sensitive, rapid ELISA kit to quantify 5-hydroxymethylcytosine in DNA with results that closely correlate to mass spectrometry analysis.
| Application | Colorimetric detection, ELISA |
|---|---|
| Assay Time | ~3 hours |
| Sensitivity | <0.02% 5-hydroxymethylcytosine DNA per 100ng input DNA (range 0.03-0.55% (100 ng/µl)) |
| Species Reactivity | Species independent |
| Alternative Name | 5-hmC |
|---|---|
| Application | ELISA, Immunoblot, IP |
| Host | Rabbit |
| Isotype | IgG1 |
| Species Reactivity | Species independent |