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Endocrinology

Highly Cited Tools for Hormone Research

Hormone Research

All multicellular organisms produce hormones, which are regulatory biochemicals parts of the endocrine system and serve as a major form of communication between different organs and tissues. Hormones regulate a variety of physiological and behavioral activities, including digestion, metabolism, respiration, tissue function, sensory perception, sleep, excretion, lactation, stress, growth and development, movement, reproduction, and mood. Among others animal hormones are classified by their chemical types (e.g. peptide- or lipid-based). The peptide hormone family includes vasopressin, insulin, luteinizing hormone (LH), follicle-stimulating hormones (FSH), and several others, while the lipid hormones family includes phospholipid-derived hormones from the arachidonic pathway (e.g. eicosanoids) and steroid hormones like testosterone and cortisol. Enzo provides a variety of high sensitivity ELISAs, high quality antibodies, and high purity biochemicals for researchers looking at hormone-related research.

Endocrinology Solutions

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Peptide Hormones

Peptide hormones are secreted from the pituitary gland. The anterior pituitary secretes important glycoproteins like follicle-stimulating hormone (FSH) and luteinizing hormone (LH) which are involved in fertility, thyroid stimulating hormone (TSH), which is involved in metabolism, adrenocorticotropic hormone (ACTH), which acts on the adrenal cortex to regulate the secretion of glucocorticoids; and growth hormone, which acts on bone, muscle, and the liver. The posterior pituitary gland secretes antidiuretic hormone or vasopressin, and oxytocin. Peptide hormones are produced by many different organs and tissues, including the pancreas (glucagon, insulin and somatostatin), the gastrointestinal tract (gastrin), and adipose tissue stores (leptin). Enzo provides a variety of high sensitivity ELISAs, high quality antibodies and high purity biochemical for researchers looking at hormone-related research.

Steroid Hormones

Steroid hormones are lipid-soluble molecules which help control metabolism, inflammation, immune functions, salt and water balance, development of sexual characteristics, and the ability to withstand illness and injury. Steroid hormones are generally synthesized from cholesterol in the gonads, placenta, and the adrenal glands. They can be grouped into five groups by the receptors to which they bind including: glucocorticoids, mineralocorticoids, androgens, estrogens, and progestins. Vitamin D derivatives are considered a related hormone system due to its homologous receptors. Enzo provides a variety of high sensitivity ELISAs, high quality antibodies, and high purity biochemical for researchers looking at hormone-related research.

Eicosanoids

Eicosanoid ELISA Kits

When inflammation is left unchecked, it can cease to be a beneficial event and contribute to the pathogenesis of numerous diseases which include rheumatoid arthritis, chronic bronchitis, emphysema, asthma, psoriasis, cancer, and colitis. Molecules in the arachidonic acid enzyme cascade play a number of important biological roles, both normal and pathological. The derivatives of arachidonic acid are known as eicosanoids, a group of biologically active oxygenated unsaturated fatty acids. They include prostaglandins, thromboxanes, leukotrienes, hydroxyeicosatetraenoic acids (HETEs), and lipoxins. Eicosanoids have been shown to enhance, as well as attenuate inflammation and have also been linked to carcinogenesis. Enzo provides a wide selection of high sensitivity ELISA kits for detection of eicosanoids, as well as small molecules, antibodies, and a bioactive lipid library for studying the role of eicosanoids in inflammation and immunity.