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Signaling Pathway Modulators
| Alternative Name | 6-Methyl-2-(phenylethynyl)-pyridine . HCl |
|---|---|
| CAS | 96206-92-7 |
| Couple Type | Inhibitor, Ligand |
| Purity | ≥99% |
| CAS | 329205-68-7 |
|---|---|
| Couple Type | Inhibitor, Ligand |
| Purity | ≥98% (HPLC) |
mTOR inhibitor WYE-132
ENZ-CHM140
Highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Antiproliferative.
| Alternative Name | 1-{4-[1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-phenyl}-3-methyl-urea, WYE-125132 |
|---|---|
| CAS | 1144068-46-1 |
| Couple Type | Inhibitor |
| Purity | ≥99% (HPLC) |
mTOR inhibitor WYE-23
ENZ-CHM136
Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.
| Alternative Name | 4-{6-[4-(3-Cyclopropyl-ureido)-phenyl]-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl}-piperidine-1-carboxylic acid methyl ester |
|---|---|
| CAS | 1062169-46-3 |
| Couple Type | Inhibitor |
| Purity | ≥99% (HPLC) |
mTOR inhibitor WYE-28
ENZ-CHM137
Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.
| Alternative Name | 4-(6-{4-[3-(4-Hydroxymethyl-phenyl)-ureido]-phenyl}-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidine-1-carboxylic acid methyl ester |
|---|---|
| CAS | 1062172-60-4 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
| Alternative Name | (1-Oxyl-2,2,5,5-tetramethylpyrroline-3-methyl) methanethiosulfonate |
|---|---|
| CAS | 81213-52-7 |
| Purity | ≥98% (HPLC) |
| Alternative Name | 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexanoic acid |
|---|---|
| CAS | 24280-93-1 |
| Couple Type | Inhibitor |
| Purity | ≥98% (HPLC) |
| Alternative Name | 3,3',4',5,5',7-Hexahydroxyflavone |
|---|---|
| CAS | 529-44-2 |
| Couple Type | Inhibitor |
| Purity | ≥90% (HPLC) |
| Alternative Name | ISP-1, Thermozymocidin, 2S,3R,4R,6E-2-Amino-3,4-dihydroxy-2-hydroxymethyl-14-oxo-6-eicosenoic acid |
|---|---|
| CAS | 35891-70-4 |
| Couple Type | Inhibitor |
| Purity | ≥98% (TLC) |
| Alternative Name | N,N-Dimethyl-D-erythro-sphingosine |
|---|---|
| CAS | 119567-63-4 |
| Couple Type | Inhibitor |
| Purity | ≥98% (TLC) |
| CAS | 312917-14-9 |
|---|---|
| Couple Type | Inhibitor |
| Purity | ≥95% (HPLC) |
| Alternative Name | ACA |
|---|---|
| CAS | 110683-10-8 |
| Couple Type | Blocker, Inhibitor |
| Purity | ≥99% (HPLC) |
