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Signal Transduction & Signaling Pathways
| Alternative Name | MAP kinase phosphatase 3, DUSP6, Dual specificity protein phosphatase 6, PYST1 |
|---|---|
| Source | Produced in Sf9 insect cells. Recombinant full length MKP-3. Produced in a baculovirus expression system. |
| Alternative Name | 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine . HCl |
|---|---|
| CAS | 110448-33-4 |
| Couple Type | Inhibitor |
| Purity | ≥99% |
| Alternative Name | 1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine . HCl |
|---|---|
| CAS | 105637-50-1 |
| Couple Type | Inhibitor |
| Purity | ≥98% (TLC) |
| Purity | ≥95% (TLC) |
|---|
| Alternative Name | CYT 387, N-(cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-benzamide |
|---|---|
| CAS | 1056634-68-4 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
| Alternative Name | MSU (crystals), Uric Acid (crystals) |
|---|---|
| CAS | 1198-77-2 |
| Couple Type | Activator |
| Alternative Name | 6-Methyl-2-(phenylethynyl)-pyridine . HCl |
|---|---|
| CAS | 96206-92-7 |
| Couple Type | Inhibitor, Ligand |
| Purity | ≥99% |
| CAS | 329205-68-7 |
|---|---|
| Couple Type | Inhibitor, Ligand |
| Purity | ≥98% (HPLC) |
| Alternative Name | mTOR (human FKBP12-rapamycin-binding domain) |
|---|---|
| Application | ChIP, ICC, WB |
| Host | Rabbit |
| Species Reactivity | Human |
mTOR inhibitor WYE-132
ENZ-CHM140
Highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Antiproliferative.
| Alternative Name | 1-{4-[1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-phenyl}-3-methyl-urea, WYE-125132 |
|---|---|
| CAS | 1144068-46-1 |
| Couple Type | Inhibitor |
| Purity | ≥99% (HPLC) |
mTOR inhibitor WYE-23
ENZ-CHM136
Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.
| Alternative Name | 4-{6-[4-(3-Cyclopropyl-ureido)-phenyl]-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl}-piperidine-1-carboxylic acid methyl ester |
|---|---|
| CAS | 1062169-46-3 |
| Couple Type | Inhibitor |
| Purity | ≥99% (HPLC) |
mTOR inhibitor WYE-28
ENZ-CHM137
Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.
| Alternative Name | 4-(6-{4-[3-(4-Hydroxymethyl-phenyl)-ureido]-phenyl}-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidine-1-carboxylic acid methyl ester |
|---|---|
| CAS | 1062172-60-4 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
| Alternative Name | (1-Oxyl-2,2,5,5-tetramethylpyrroline-3-methyl) methanethiosulfonate |
|---|---|
| CAS | 81213-52-7 |
| Purity | ≥98% (HPLC) |
| Alternative Name | 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexanoic acid |
|---|---|
| CAS | 24280-93-1 |
| Couple Type | Inhibitor |
| Purity | ≥98% (HPLC) |
