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Proteases
| Alternative Name | Matrix metalloproteinase 7, Matrilysin, Pump |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in E. coli. Active Matrix Metalloproteinase-7 (MMP-7, matrilysin, pump) catalytic domain from human cDNA. The enzyme consists of the catalytic domain of human MMP-7 (Tyr95-Lys267, NM_002423) with a C-terminal purification tag. |
| Alternative Name | Matrix metalloproteinase 8, Neutrophil collagenase, Collagenase-2 |
|---|---|
| Purity | ≥90% (SDS-PAGE) |
| Source | Produced in E. coli. Active Matrix Metalloproteinase-8 (MMP-8, neutrophil collagenase, collagenase-2) catalytic domain from human cDNA. The enzyme consists of the catalytic domain of human MMP-8 (Phe99-Gln269, NM_002424) with a C-terminal purification tag. This represents a naturally-occurring active form of MMP-8 which lacks the C-terminal hemopexin domain1. MMPs lacking this domain cannot cleave native collagens; however, activity toward other targets such as gelatin, casein, or peptide substrates is unaffected. |
| Alternative Name | Matrix metalloproteinase 8, Neutrophil collagenase, Collagenase-2 |
|---|---|
| Purity | ≥90% (SDS-PAGE) |
| Source | Isolated from stimulated human neutrophil granulocytes (buffy coat). Requires activation. |
| Alternative Name | Matrix metalloproteinase 9, Gelatinase B, 92 kDa Type IV collagenase |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in E. coli. Active recombinant matrix metalloproteinase-9 (MMP-9, gelatinase B, 92 kDa type IV collagenase) cloned from human cDNA. The enzyme consists of residues Phe107-Pro449 (NM_004994), which comprises the catalytic/fibronectin domain of human MMP-9, with a C-terminal purification tag. This represents a naturally-occurring active form of MMP-9 which lacks the C-terminal hemopexin domain. Activity toward its targets, such as gelatin, casein, or peptide substrates, is unaffected. |
| Alternative Name | Matrix metalloproteinase 9, Gelatinase B, 92kDa Type IV collagenase |
|---|---|
| Purity | ≥95% (SDS-PAGE, Western blot) |
| Source | Isolated from stimulated human neutrophil granulocytes (buffy coat). Disulfide-bridged MMP-9 homodimer. |
| Alternative Name | 2-(N-benzyl-4-methoxyphenylsulfonamido)-5-((diethylamino)methyl)-N-hydroxy-3-methylbenzamide |
|---|---|
| CAS | 206549-55-5 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
| Purity | ≥97% (HPLC) |
|---|
| Purity | ≥97% (HPLC) |
|---|---|
| Source | Produced in E. coli. |
| CAS | 82956-11-4 |
|---|---|
| Couple Type | Inhibitor |
| Purity | ≥98% (HPLC) |
| Alternative Name | NEP, Neutral endopeptidase 24.11, Enkephalinase, CALLA, Common acute lymphoblastic leukemia antigen, CD10 |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in Sf9 insect cells. Produced in a baculovirus expression system. |
Neutrophil elastase (human), (purified)
BML-SE284
Major inflammatory protease released by neutrophils
| Alternative Name | Leukocyte elastase, LE |
|---|---|
| Purity | ≥95% (SDS-PAGE). Although this is in highly purified form, and the source material tested negative for HbsAg, anti-HBc, anti-HCV, and anti-HIV-1 and -2, handle this product with all due precautions. |
| Source | Isolated from human neutrophils. Active enzyme. |
| Application | Activity assay, Colorimetric detection, HTS |
|---|