PI(3)K-Akt-mTOR Pathway

 

Filters By

(0)
Filter By
Clear Filters
Product Types

All Products

16 out of 76 results

Inositol 1,4,5-trisphosphate receptor (type-I) polyclonal antibody

ALX-210-169

Alternative Name IP3 receptor type-I, IP3R-I, ITPR1, INSP3R1, IP3R1
Application ICC, IHC (FS), IP, WB
Host Rabbit
Species Reactivity Dog, Mouse, Rat

IP3 receptor type 1 polyclonal antibody

BML-SA254

Alternative Name IP3R1, ITPR1, IP3R-I, Inositol 1,4,5-triphosphate receptor type 1, INSP3R1
Application IHC, WB
Host Rabbit
Species Reactivity Dog, Human, Rat

Ku-0063794

ENZ-CHM135

Highly selective and potent inhibitor against both mTORC1 and mTORC2.

Alternative Name rel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol, mTOR Inhibitor IV
CAS 938440-64-3
Couple Type Inhibitor
Purity ≥99% (HPLC)

L-α-Phosphatidylinositol-3,4,5-P3 . 7Na

BML-PH107

PKC substrate

2 citations

Alternative Name PtdIns(3,4,5)P3, (1,2-dipalmitoyl)-, 1,2-Dipalmitoyl-sn-glycero-3-phospho-1-D-myo-inositol-3,4,5-trisphosphate . 7Na
Couple Type Substrate
Purity ≥98% (TLC)

L-α-Phosphatidylinositol-3,4-P2

BML-PH106

Activator of PKC and Akt

3 citations

Couple Type Activator
Purity ≥98% (NMR)

LY 294002

BML-ST420

PI3 kinase inhibitor

50 citations

Alternative Name 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
CAS 154447-36-6
Couple Type Inhibitor
Purity ≥98% (HPLC)

LY-303,511

ALX-270-410

2 citations

Alternative Name 2-(4-Piperazinyl)-8-phenyl-4H-1-benzopyran-4-one
CAS 154447-38-8
Purity ≥95% (HPLC)

MK-2206 . 2HCl

ENZ-CHM164

Highly selective inhibitor of Akt1, Akt2 and Akt3

4 citations

CAS 1032350-13-2
Couple Type Inhibitor
Purity ≥99% (HPLC)

ML-9

BML-EI153

Myelin basic protein inhibitor

9 citations

Alternative Name 1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine . HCl
CAS 105637-50-1
Couple Type Inhibitor
Purity ≥98% (TLC)

mTOR (human FRB Domain) polyclonal antibody

ALX-215-065

19 citations

Alternative Name mTOR (human FKBP12-rapamycin-binding domain)
Application ChIP, ICC, WB
Host Rabbit
Species Reactivity Human

mTOR inhibitor WYE-132

ENZ-CHM140

Highly potent, ATP-competitive, and specific mTOR kinase inhibitor. Antiproliferative.

Alternative Name 1-{4-[1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-4-(8-oxa-3-aza-bicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-phenyl}-3-methyl-urea, WYE-125132
CAS 1144068-46-1
Couple Type Inhibitor
Purity ≥99% (HPLC)

mTOR inhibitor WYE-23

ENZ-CHM136

Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.

Alternative Name 4-{6-[4-(3-Cyclopropyl-ureido)-phenyl]-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl}-piperidine-1-carboxylic acid methyl ester
CAS 1062169-46-3
Couple Type Inhibitor
Purity ≥99% (HPLC)

mTOR inhibitor WYE-28

ENZ-CHM137

Cell-permeable, potent, selective, and ATP-competitive mTOR inhibitor.

Alternative Name 4-(6-{4-[3-(4-Hydroxymethyl-phenyl)-ureido]-phenyl}-4-morpholin-4-yl-pyrazolo[3,4-d]pyrimidin-1-yl)-piperidine-1-carboxylic acid methyl ester
CAS 1062172-60-4
Couple Type Inhibitor
Purity ≥97% (HPLC)

Omentin (rat), (recombinant)

ALX-522-132

1 citation

Alternative Name Intelectin-1, Endothelial lectin HL-1, Intestinal lactoferrin receptor, Galactofuranose-binding lectin
Purity ≥95% (SDS-PAGE)
Source Produced in HEK 293 cells. Rat omentin (aa 20-313) is fused at the N-terminus to a FLAG®-tag.

Omentin 1 (human), (recombinant)

ALX-522-108

5 citations

Alternative Name Intelectin-1, Endothelial lectin HL-1, Intestinal lactoferrin receptor, Galactofuranose-binding lectin
Purity ≥95% (SDS-PAGE)
Source Produced in HEK 293 cells. Human omentin 1 (intelectin-1) (aa 17-313) is fused at the N-terminus to a FLAG®-tag.

p70 S6 kinase (human), (recombinant)

BML-SE345

Alternative Name p70 S6K
Source Produced in insect cells. Active, full length p70 S6K. Produced in a baculovirus expression system.