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Cell Organelles & Structures
| Alternative Name | Matrix metalloproteinase 2, Gelatinase A, 72 kDa Type IV collagenase |
|---|---|
| Source | Isolated from mouse fibroblasts. Primarily latent form. |
| Alternative Name | Matrix metalloproteinase 2, Gelatinase A, 72 kDa Type IV collagenase |
|---|---|
| Purity | ≥90% (SDS-PAGE, Western blot) |
| Source | Isolated from human rheumatoid synovial fibroblasts. Requires activation. |
| Alternative Name | Matrix metalloproteinase 20, Enamelysin |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in E. coli. Active recombinant matrix metalloproteinase-20 (MMP-20, enamelysin) cloned from human cDNA. The enzyme consists of residues Tyr108-Phe276 (NM_004771), which comprises the catalytic domain of human MMP-20, with a C-terminal purification tag. This represents a naturally-occurring active form of MMP-20 which lacks the C-terminal hemopexin domain. |
| Alternative Name | Matrix metalloproteinase 3, Stromelysin-1, Transin-1 |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in E. coli. Active Matrix Metalloproteinase-3 (MMP-3, stromelysin-1, transin) catalytic domain from human cDNA. The enzyme consists of the catalytic domain of human MMP-3 (Phe100-Thr272, NM_002422) with a C-terminal purification tag. |
| Alternative Name | Matrix metalloproteinase 7, Matrilysin, Pump |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in E. coli. Active Matrix Metalloproteinase-7 (MMP-7, matrilysin, pump) catalytic domain from human cDNA. The enzyme consists of the catalytic domain of human MMP-7 (Tyr95-Lys267, NM_002423) with a C-terminal purification tag. |
| Alternative Name | Matrix metalloproteinase 8, Neutrophil collagenase, Collagenase-2 |
|---|---|
| Purity | ≥90% (SDS-PAGE) |
| Source | Produced in E. coli. Active Matrix Metalloproteinase-8 (MMP-8, neutrophil collagenase, collagenase-2) catalytic domain from human cDNA. The enzyme consists of the catalytic domain of human MMP-8 (Phe99-Gln269, NM_002424) with a C-terminal purification tag. This represents a naturally-occurring active form of MMP-8 which lacks the C-terminal hemopexin domain1. MMPs lacking this domain cannot cleave native collagens; however, activity toward other targets such as gelatin, casein, or peptide substrates is unaffected. |
| Alternative Name | Matrix metalloproteinase 8, Neutrophil collagenase, Collagenase-2 |
|---|---|
| Purity | ≥90% (SDS-PAGE) |
| Source | Isolated from stimulated human neutrophil granulocytes (buffy coat). Requires activation. |
| Alternative Name | Matrix metalloproteinase 9, Gelatinase B, 92 kDa Type IV collagenase |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in E. coli. Active recombinant matrix metalloproteinase-9 (MMP-9, gelatinase B, 92 kDa type IV collagenase) cloned from human cDNA. The enzyme consists of residues Phe107-Pro449 (NM_004994), which comprises the catalytic/fibronectin domain of human MMP-9, with a C-terminal purification tag. This represents a naturally-occurring active form of MMP-9 which lacks the C-terminal hemopexin domain. Activity toward its targets, such as gelatin, casein, or peptide substrates, is unaffected. |
| Alternative Name | Matrix metalloproteinase 9, Gelatinase B, 92kDa Type IV collagenase |
|---|---|
| Purity | ≥95% (SDS-PAGE, Western blot) |
| Source | Isolated from stimulated human neutrophil granulocytes (buffy coat). Disulfide-bridged MMP-9 homodimer. |
| Alternative Name | 2-(N-benzyl-4-methoxyphenylsulfonamido)-5-((diethylamino)methyl)-N-hydroxy-3-methylbenzamide |
|---|---|
| CAS | 206549-55-5 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
| Alternative Name | 4-(3-Hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4H-pyrimidin-5-carboxylic acid ethyl ester |
|---|---|
| CAS | 329689-23-8 |
| Couple Type | Inhibitor |
| Purity | ≥98% (TLC) |
| Alternative Name | Mortalin, Heat shock protein 70 (mitochondrial), GRP75 |
|---|---|
| Application | ICC, IP, WB |
| Host | Mouse |
| Isotype | IgG3 |
| Species Reactivity | Dog, Human, Monkey, Mouse |
| Application | IHC (PS), WB |
|---|---|
| Host | Mouse |
| Isotype | IgG1 |
| Species Reactivity | Human, Monkey, Rabbit |
