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Autophagy System
| Alternative Name | Phosphatase and tensin homolog deleted on chromosome 10 |
|---|---|
| Purity | ≥80% (SDS-PAGE) |
| Source | Produced in E. coli. Full length human PTEN (aa 1-403) is fused at the N-terminus to a His-tag. |
| Alternative Name | Phosphatase and tensin homolog deleted on chromosome 10 |
|---|---|
| Application | ELISA, ICC, IHC, IP, WB |
| Host | Mouse |
| Isotype | IgG2a kappa |
| Species Reactivity | Human, Monkey, Rat |
| Alternative Name | trans-3,5-Dimethoxy-4’-hydroxystilbene |
|---|---|
| CAS | 537-42-8 |
| Couple Type | Inhibitor |
| Purity | ≥98% (HPLC) |
| Alternative Name | 3,3',4',5,7-Pentahydroxyflavone . 2H2O |
|---|---|
| CAS | 6151-25-3 |
| Couple Type | Activator, Inhibitor |
| Purity | ≥95% (HPLC) |
| Alternative Name | Ras-related protein Rab-7a |
|---|---|
| Application | ICC, IF, IHC (PS) |
| Host | Rabbit |
| Isotype | IgG |
| Species Reactivity | Human |
| Purity | ≥90% (SDS-PAGE) |
|---|---|
| Source | Produced in E. coli.. Residues 418-587 of RanGAP1 fused to an N-terminal GST tag. |
Rapamycin
BML-A275
An mTOR inhibitor that modulates cell growth, proliferation, and autophagy - frequently used in signaling pathway research and immunosuppressive studies.
| Alternative Name | Sirolimus, AY-22,989, RAPA, Rapamune |
|---|---|
| CAS | 53123-88-9 |
| Couple Type | Inhibitor, Ligand |
| Purity | ≥98% (HPLC) |
| Alternative Name | trans-3,4',5-Trihydroxystilbene |
|---|---|
| CAS | 501-36-0 |
| Couple Type | Activator, Inhibitor, Ligand |
| Purity | ≥98% (HPLC) |
| Alternative Name | Reactivation of p53 and Induction of Tumor Cell Apoptosis, 2,5-bis(5-Hydroxymethyl-2-thienyl)furan, NSC652287 |
|---|---|
| CAS | 213261-59-7 |
| Purity | ≥98% (HPLC) |
| Alternative Name | Mallotoxin |
|---|---|
| CAS | 82-08-6 |
| Couple Type | Inhibitor |
| Purity | ≥98% (HPLC) |
SCREEN-WELL® Autophagy library
BML-2837
Structurally and mechanistically different compounds for studying the roles of pro- and anti-autophagic molecules in cells and in vitro applications.
| Alternative Name | 6-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-N-hydroxyhexanamide |
|---|---|
| CAS | 287383-59-9 |
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
| Alternative Name | D-3-Deoxy-2-O-methyl-myo-inositol 1-[(R)-2-methoxy-3-(octadecyloxy)propyl hydrogen phosphate] |
|---|---|
| Couple Type | Inhibitor |
| Purity | ≥98% (TLC) |
| Alternative Name | Sirtuin-1 |
|---|---|
| Application | IHC (PS), WB |
| Host | Rabbit |
| Species Reactivity | Human |
| Alternative Name | Sirtuin 1 |
|---|---|
| Source | Produced in E. coli. Recombinant SIRT1 from human cDNA containing an N-terminal His-tag. |