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Apoptosis Signaling
| CAS | 6894-43-5 |
|---|---|
| Couple Type | Activator |
| Purity | ≥97% (UHPLC) |
KillerTRAIL™ Protein (soluble) (human), (recombinant)
ALX-201-073
Enhanced ligand that utilizes the proprietary Killer™ linker peptide that promotes stability.
| Alternative Name | Apo-2L, TNFSF 10, CD253 |
|---|---|
| Purity | ≥99% (SDS-PAGE, MS analysis) |
| Source | Produced in E. coli. The extracellular domain of human TRAIL (aa 95-281) is fused at the N-terminus to a His-tag and a linker peptide. |
| Alternative Name | Apo-2L, TNFSF 10, CD253 |
|---|---|
| Purity | ≥98% (SDS-PAGE) |
| Source | Produced in E. coli. The extracellular domain of human TRAIL (aa 95-281) is fused at the N-terminus to a His-tag and a linker peptide. |
| Alternative Name | (E)-3-[5-(1,1-Dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one |
|---|---|
| CAS | 58749-22-7 |
| Purity | ≥96% (HPLC) |
| Alternative Name | HVEML, TNFSF 14, CD258 |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in HEK 293 cells. The extracellular domain of human LIGHT (aa 89-240) is fused at the N-terminus to a linker peptide (10 aa) and a FLAG®-tag. |
| Alternative Name | Lymphotoxin-β receptor, TNFRSF 3, Tumor necrosis factor receptor 2 related protein, Tumor necrosis factor C receptor, Tumor necrosis factor receptor superfamily member 3 [precursor] |
|---|---|
| Application | Flow Cytometry |
| Host | Rat |
| Isotype | IgG2a |
| Species Reactivity | Mouse |
| Alternative Name | Bcl-2-like protein 3 |
|---|---|
| Application | IF, IHC (PS), WB |
| Host | Rabbit |
| Species Reactivity | Dog, Guinea pig, Human, Monkey, Porcine, Rabbit |
| Alternative Name | Helicard, Melanoma differentiation-associated gene 5, Interferon-induced helicase C domain-containing protein 1, RH116, CADM-140 autoantigen, RIG-I-like receptor 2, RLR-2 |
|---|---|
| Application | ELISA, IP, WB |
| Host | Mouse |
| Isotype | IgG1 |
| Species Reactivity | Human |
| Alternative Name | Helicard, Melanoma differentiation-associated gene 5, Interferon-induced helicase C domain-containing protein 1, RH116, CADM-140 autoantigen, RIG-I-like receptor 2, RLR-2 |
|---|---|
| Application | IP, WB |
| Host | Rabbit |
| Species Reactivity | Human |
| Alternative Name | Helicard, Melanoma differentiation-associated gene 5, Interferon-induced helicase C domain-containing protein 1, RH116, CADM-140 autoantigen, RIG-I-like receptor 2, RLR-2 |
|---|---|
| Application | ELISA, WB |
| Host | Mouse |
| Isotype | IgG1 |
| Species Reactivity | Human, Mouse |
| Alternative Name | Helicard, Melanoma differentiation-associated gene 5, Interferon-induced helicase C domain-containing protein 1, RH116, CADM-140 autoantigen, RIG-I-like receptor 2, RLR-2 |
|---|---|
| Application | ELISA, IF, IHC (PS), WB |
| Host | Rabbit |
| Isotype | IgG |
| Species Reactivity | Human, Mouse |
| CAS | 338967-87-6 |
|---|---|
| Couple Type | Inhibitor |
| Purity | ≥97% (HPLC) |
MEGACD40L® Protein (soluble) (human), (recombinant)
ALX-522-110
High activity, high purity CD40L protein for co-stimulatory activation of an immune response
| Alternative Name | CD40L:ACRP30headless, CD154:ACRP30headless, TNFSF 5:ACRP30headless, gp39:ACRP30headless |
|---|---|
| Purity | ≥90% (SDS-PAGE) |
| Source | Produced in CHO cells. The extracellular domain of human CD40L (CD154) (aa 116-261) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag. |
MEGACD40L® Protein (soluble) (mouse), (recombinant)
ALX-522-120
High activity, high purity CD40L protein for co-stimulatory activation of an immune response
| Alternative Name | CD40L:ACRP30headless, CD154:ACRP30headless, TNFSF5:ACRP30headless, gp39:ACRP30headless |
|---|---|
| Purity | ≥95% (SDS-PAGE) |
| Source | Produced in CHO cells. The extracellular domain of mouse CD40L (CD154) (aa 115-260) is fused at the N-terminus to mouse ACRP30headless (aa 18-111) and a FLAG®-tag. |
