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Discussion of Fiscal 2005 First Quarter Operating Results

For:                  ENZO BIOCHEM, INC. (NYSE:ENZ)
 
To:                   Interested Members of the Investment Community
 
Subject:            Discussion of Fiscal 2005 First Quarter Operating Results
 
                                                                           with
 
BARRY WEINER, President
and
DEAN ENGELHARDT, Ph.D., Executive Vice President
 
 
Date:                Monday, December 13, 2004
 
Time:                8:30 A.M. (Eastern Time)
 
Dial-In Number for Teleconference: (877) 780-2271. International callers dial: (973) 582-2737.   To listen, please dial in approximately ten minutes prior to the scheduled teleconference time.
 
Replay: Dial (877) 519-4471; you will be prompted for PIN number 5484581. International callers dial (973) 341-3080 and use the same PIN number. The replay will be available from Monday December 13 at 11:00 AM (E.T.) until Midnight December 27, 2004.
 
The conference call can also be heard over the Internet at http://www.vcall.com.   To listen to the live call, please go to the web site at least fifteen minutes early to register, download and install any necessary audio software.   A replay will be available approximately two hours after the call.